Ongoing Projects

Discovery and Development of Health Products: Disease-Specific Bioactive Hits from Terrestrial Organisms: Confirmatory and Orthogonal Assays to Eliminate Artefactual Drug Bioactivities (Phase 3): Continuing Needs of the Tuklas Lunas Program

UP Diliman

Tuklas Lunas

Studies and Correlation Analyses of Chemical Composition and Bioactivity of three (3) common Philippine Botanial Plants: Antipyretic, Anti-inflammatory, Analgesic Activity of Extracts from Vitex negundo L. and Zingiber officinale Roscoe, and Antimicrobial Activity of Blumea Balsamifera Extract

Synnovate Pharma Corporation

Tuklas Lunas

Microwave-Assisted Synthesis, Characterization and Molecular Docking Studies of Quinoline-4-Carboxylic Acids and Hydrazide Isosteres with Antitubercular Activity

University of Santo Tomas

Tuklas Lunas

Tuklas Lunas Consortium in the Cordillera: Documentation, Standardization, and Formulation of Dosage Forms from Indigenous Plants and Microorganisms with Bioactivities: Project 6. The formulation & evaluation of capsules containing herbals with antidiabetic activity

Saint Louis University

Tuklas Lunas

Tuklas Lunas Consortium in the Cordillera: Documentation, Standardization, and Formulation of Dosage Forms from Indigenous Plants and Microorganisms with Bioactivities: Project 1. Potential activity of indigenous and endemic plant extracts from the Cordillera region against ESKAPE bacteria

UP Baguio

Tuklas Lunas

Potential Anti-Cancer Leads from Plants in Region XII (USM-TLDC): Project 1: Screening of plants from Region XII with Potential Anti-Cancer Activity

University of Southern Mindanao

Tuklas Lunas

Discovery and Development of Natural Products from Mindanao Marine Resources: Project 1. Anti-Cancer Drug Leads from Marine Sponges Collected Off the Coasts of Mindanao

MSU-IIT

Tuklas Lunas

PHARMAFERN: Development of Health Products from Ferns: Project 5. Anti-inflammatory Compound/s from Select Ferns in Mindanao

Central Mindanao University

Tuklas Lunas

Metabolomics-driven Discovery of Antimicrobial Drug Leads and Anticancer Screening of Extracts from Marine Sediment-Derived Actinomycetes of Iloilo

University of San Agustin

Tuklas Lunas

Development of Anti-inflammatory Herbal Products from Iluko Indigenous Plants: Project 3. Formulation Dosage Forms from Standardized Non-toxic Bioactive Extracts from Indigenous Plants

Mariano Marcos State University

Tuklas Lunas

Philippine Biorepository Network: Development of Biobanking Facility for Plant Extracts/Compounds for Drug Discovery

UP Diliman

Tuklas Lunas

DDHP: Marine Component Phase 2: Project 2. Anti-Infective and Anti-Cancer Drug Candidates from Marine Microorganisms and Sponges: Discovery and Development

UP Diliman

Tuklas Lunas

DDHP: Marine Component Phase 2: Project 1. Anti-Pain and Anti-Neurodegeneration Drug Candidates: Discovery and Development

UP Diliman

Tuklas Lunas

Bridging Efficacy and Safey: IND-enabling Suite of ADMETox Assays: Project 5. Determination of Pharmacokinetic Properties

Pharmalytics Corporation

Tuklas Lunas

Bridging Efficacy and Safey: IND-enabling Suite of ADMETox Assays: Project 4. Metabolite Profiling Using Imaging Mass Spectrometry

University of San Agustin

Tuklas Lunas

Bridging Efficacy and Safey: IND-enabling Suite of ADMETox Assays: Project 3. HPLC and Mass Spectral Studies to Support Various ADMET assays

UP Diliman

Tuklas Lunas

Bridging Efficacy and Safey: IND-enabling Suite of ADMETox Assays: Project 2. Cell-based ADMET assays

UP Diliman

Tuklas Lunas

Bridging Efficacy and Safey: IND-enabling Suite of ADMETox Assays Project 1. Optimization of Physico-Chemical Drug Properties

UP Diliman

Tuklas Lunas

Synthesis and Derivatization of Disease-specific Bioactive Hits and Lead Compounds (Phase II) Project 6. Computer-Aided Drug Design of Natural Products-Based, and Synthetic Antidiabetic, Antifungal, and Anticancer Lead Compounds and Derivatives

UP Diliman

Tuklas Lunas

Synthesis and Derivatization of Disease-specific Bioactive Hits and Lead Compounds (Phase II): Project 5. Lead Optimization of Acrylated Cyclopentenone Derivatives with Anti-Inflammatory and Anti-Cancer Activities: Synthesis, Characterization, SAR and ADMETox Studies

University of Santo Tomas

Tuklas Lunas

Synthesis and Derivatization of Disease-specific Bioactive Hits and Lead Compounds (Phase II): Project 4. Lead Optimization, Molecular Docking and Determination of ADME-Tox Properties of Benzimidazoles with Antihypertensive Activity

MSU-IIT

Tuklas Lunas

Synthesis and Derivatization of Disease-specific Bioactive Hits and Lead Compounds (Phase II): Project 3. Synthesis of Deguelin, Rotenone, and Small Molecule Derivatives as Anticancer Agents

UP Diliman

Tuklas Lunas

Synthesis and Derivatization of Disease-specific Bioactive Hits and Lead Compounds (Phase II): Project 2. Molecular Docking and ADME-Tox–guided Synthesis of Azole-Based Anti-Infective Agents

UP Diliman

Tuklas Lunas

Synthesis and Derivatization of Disease-specific Bioactive Hits and Lead Compounds (Phase II): Project 1. Lead Optimization, In Silico Prediction, Molecular Docking and Determination of ADMETox Properties of Small Molecules as Antidiabetic Drugs

UP Diliman

Tuklas Lunas

Discovery and Development of Health Products (DDHP): Disease-Specific Bioactive Hits from Terrestrial Organisms Project 11. De-replication with LC-MS Based Metabolomics

UP Diliman

Tuklas Lunas

Discovery and Development of Health Products (DDHP): Disease-Specific Bioactive Hits from Terrestrial Organisms: Project 10. Anti-hyperuricemic bioactive hits from priority plant extracts

Pascual Laboratories, Inc.

Tuklas Lunas

Discovery and Development of Health Products (DDHP): Disease-Specific Bioactive Hits from Terrestrial Organisms: Project 9. Anti-Lung Cancer Bioactive Hits from Priority Bioactive Extracts

UP Mindanao

Tuklas Lunas

Discovery and Development of Health Products (DDHP): Disease-Specific Bioactive Hits from Terrestrial Organisms: Project 8. Anti-diabetic Bioactive Hits from Priority Bioactive Extracts from Plants Indigenous to Benguet

Benguet State University

Tuklas Lunas

Discovery and Development of Health Products (DDHP): Disease-Specific Bioactive Hits from Terrestrial Organisms: Project 7. Anti-infective Hits from Priority Bioactive Extracts from Fungi

UP Baguio

Tuklas Lunas

Discovery and Development of Health Products (DDHP): Disease-Specific Bioactive Hits from Terrestrial Organisms: Project 6. Anti-infective Hits from Priority Bioactive Extracts from Indigenous and Endemic Plants of the Cordillera Against Staphylococcus aureus and Pseudomonas aeruginosa

UP Baguio

Tuklas Lunas

Discovery and Development of Health Products (DDHP): Disease-Specific Bioactive Hits from Terrestrial Organisms: Project 5. Potential Anticancer Bioactive Hits from Priority Bioactive Extracts against Breast Cancer Cell Lines

UP Manila

Tuklas Lunas

Discovery and Development of Health Products (DDHP): Disease-Specific Bioactive Hits from Terrestrial Organisms: Project 4. Anti-infective Bioactive Hits Against Methicillin-Resistant Staphylococcus aureus and Klebsiella pneumoniae from Priority Bioactive Extracts

UP Manila

Tuklas Lunas

Compounds Active Against Cancer Lines (HCT116, MCF7, A549) from Priority Extracts – Phase II

UP Diliman

Tuklas Lunas

Myko-mining and Myko-pharming of Wild Edible and Poisonous Mushrooms in Luzon Island, Philippines for their Medicinal Properties (Phase III) Project 1. Mykopharming of Wild Edible and Poisonous Mushrooms for Their Medicinal Properties

Central Luzon State University

Tuklas Lunas

Discovery and Development of Health Products [DDHP]: Formulation, Standardization, and Metabolic Profiling of Disease-Specific Top-Tier Plants for Pre-Clinical and Clinical Development Project 4. Chemical standardization of top-tier plant extracts for diabetes, inflammation, and cancer using high performance thin layer chromatography

Pascual Laboratories, Inc.

Tuklas Lunas

Discovery and Development of Health Products [DDHP]: Formulation, Standardization, and Metabolic Profiling of Disease-Specific Top-Tier Plants for Pre-Clinical and Clinical Development Project 3. Standardized Dosage Forms of Biologically Active Extracts Suitable for Use in Pre-clinical and Clinical Research: Top Tier Herbs for Cancer

UP Diliman

Tuklas Lunas

Discovery and Development of Health Products [DDHP]: Formulation, Standardization, and Metabolic Profiling of Disease-Specific Top-Tier Plants for Pre-Clinical and Clinical Development Project 2. Standardized Dosage Forms of Biologically Active Extracts Suitable for Use in Preclinical and Clinical Research: Top Tier Herbs for Diabetes, Inflammation and Cancer

Pharmalytics Corporation

Tuklas Lunas

Efficacy and Safety of Orally Administered Fixed-Dose Combination Capsule of RGA02 + JRA01 + ASB02 in the Treatment of Dengue Without Warning Signs Among Adult Filipinos in Cavite: A Randomized, Double-blind, Placebo Controlled Trial

Pharmalytics Corporation

Tuklas Lunas

Project 1: Science-Based Clinical Research Management Practices

University of San Carlos

Tuklas Lunas

Discovery of Cardiometabolic Bioactives from Plants in Central Philippines (USC-TLDC Phase 2):Project 7. In vitro Cardiometabolic Activity and Toxicity Monitoring of Product Development Samples and Screening of New Herbals

University of San Carlos

Tuklas Lunas

Discovery of Cardiometabolic Bioactives from Plants in Central Philippines (USC-TLDC Phase 2): Project 5. Formulation Studies of Spray-dried Extracts from Plants with Antihyperglycemic Activity

University of San Carlos

Tuklas Lunas

Discovery of Cardiometabolic Bioactives from Plants in Central Philippines (USC-TLDC Phase 2):Project 3. Chemical Standardization of the Raw Material, Spray-dried Extracts and Dosage Forms from Selected Plants with Antihyperglycemic Activity

University of San Carlos

Tuklas Lunas

Establishment of the Visayas NMR Laboratory: Enabling the countryside with the power of magnetic resonance for drug discovery and a forward-looking pandemic response

University of San Agustin

Tuklas Lunas

Discovery and Development of Health Products [DDHP]: Formulation, Standardization, and Metabolic Profiling of Disease-Specific Top-Tier Plants for Pre-Clinical and Clinical Development:Project 1. Standardized dosage forms of biologically active extracts suitable for use in pre-clinical and clinical research: top tier herbs for diabetes and inflammation

Herbanext Laboratories, Inc.

Tuklas Lunas

Structure Identification of Anti-inflammatory and Anti-Pain Agents from Priority Extracts (Phase 4)

UP Diliman

Tuklas Lunas

Anti-inflammatory and Anti-diabetic compounds from top-tier bioactive extracts

UP Diliman

Tuklas Lunas

Formulation Quality Control and Stability Studies on Immediate-Release Tablets of Fixed-Dose Combinations of Cliostazol and Aspirin

Adamson University / Compact Pharmaceutical

Tuklas Lunas

Chemical and Biological Characterization of Pure and Bioactive Compounds from Kadios (Cajanus cajan) Seeds and its Topical Formulation Studies

UP Manila

Tuklas Lunas

Standardized and Safe Tawa-tawa: Filling in the Final Gaps for a Clinically-proven Nutraceutical Product

University of San Agustin

Tuklas Lunas

Nanostructured Herbal Extract of Momordica charantia (Bitter Melon/Ampalaya), Allium sativum (Garlic) and Curcuma longa L. (Turmeric) as Antidiabetic Agents

ITDI

Tuklas Lunas

Semi-Purification of Crude Plant Extract: An Essential Step for the Production of Pharmaceutical-Grade Ingredients

Herbanext Laboratories, Inc.

Tuklas Lunas