Ongoing Projects

Bridging Efficacy and Safey: IND-enabling Suite of ADMETox Assays: Project 5. Determination of Pharmacokinetic Properties

Pharmalytics Corporation

Tuklas Lunas

Bridging Efficacy and Safey: IND-enabling Suite of ADMETox Assays: Project 4. Metabolite Profiling Using Imaging Mass Spectrometry

University of San Agustin

Tuklas Lunas

Bridging Efficacy and Safey: IND-enabling Suite of ADMETox Assays: Project 3. HPLC and Mass Spectral Studies to Support Various ADMET assays

UP Diliman

Tuklas Lunas

Bridging Efficacy and Safey: IND-enabling Suite of ADMETox Assays: Project 2. Cell-based ADMET assays

UP Diliman

Tuklas Lunas

Bridging Efficacy and Safey: IND-enabling Suite of ADMETox Assays Project 1. Optimization of Physico-Chemical Drug Properties

UP Diliman

Tuklas Lunas

Synthesis and Derivatization of Disease-specific Bioactive Hits and Lead Compounds (Phase II) Project 6. Computer-Aided Drug Design of Natural Products-Based, and Synthetic Antidiabetic, Antifungal, and Anticancer Lead Compounds and Derivatives

UP Diliman

Tuklas Lunas

Synthesis and Derivatization of Disease-specific Bioactive Hits and Lead Compounds (Phase II): Project 5. Lead Optimization of Acrylated Cyclopentenone Derivatives with Anti-Inflammatory and Anti-Cancer Activities: Synthesis, Characterization, SAR and ADMETox Studies

University of Santo Tomas

Tuklas Lunas

Synthesis and Derivatization of Disease-specific Bioactive Hits and Lead Compounds (Phase II): Project 4. Lead Optimization, Molecular Docking and Determination of ADME-Tox Properties of Benzimidazoles with Antihypertensive Activity

MSU-IIT

Tuklas Lunas

Synthesis and Derivatization of Disease-specific Bioactive Hits and Lead Compounds (Phase II): Project 3. Synthesis of Deguelin, Rotenone, and Small Molecule Derivatives as Anticancer Agents

UP Diliman

Tuklas Lunas

Synthesis and Derivatization of Disease-specific Bioactive Hits and Lead Compounds (Phase II): Project 2. Molecular Docking and ADME-Tox–guided Synthesis of Azole-Based Anti-Infective Agents

UP Diliman

Tuklas Lunas

Synthesis and Derivatization of Disease-specific Bioactive Hits and Lead Compounds (Phase II): Project 1. Lead Optimization, In Silico Prediction, Molecular Docking and Determination of ADMETox Properties of Small Molecules as Antidiabetic Drugs

UP Diliman

Tuklas Lunas

Discovery and Development of Health Products (DDHP): Disease-Specific Bioactive Hits from Terrestrial Organisms Project 11. De-replication with LC-MS Based Metabolomics

UP Diliman

Tuklas Lunas

Discovery and Development of Health Products (DDHP): Disease-Specific Bioactive Hits from Terrestrial Organisms: Project 10. Anti-hyperuricemic bioactive hits from priority plant extracts

Pascual Laboratories, Inc.

Tuklas Lunas

Discovery and Development of Health Products (DDHP): Disease-Specific Bioactive Hits from Terrestrial Organisms: Project 9. Anti-Lung Cancer Bioactive Hits from Priority Bioactive Extracts

UP Mindanao

Tuklas Lunas

Discovery and Development of Health Products (DDHP): Disease-Specific Bioactive Hits from Terrestrial Organisms: Project 8. Anti-diabetic Bioactive Hits from Priority Bioactive Extracts from Plants Indigenous to Benguet

Benguet State University

Tuklas Lunas

Discovery and Development of Health Products (DDHP): Disease-Specific Bioactive Hits from Terrestrial Organisms: Project 7. Anti-infective Hits from Priority Bioactive Extracts from Fungi

UP Baguio

Tuklas Lunas

Discovery and Development of Health Products (DDHP): Disease-Specific Bioactive Hits from Terrestrial Organisms: Project 6. Anti-infective Hits from Priority Bioactive Extracts from Indigenous and Endemic Plants of the Cordillera Against Staphylococcus aureus and Pseudomonas aeruginosa

UP Baguio

Tuklas Lunas