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MD-PhD student publications hit record peak amid COVID-19 pandemic
Student outputs rise to record-high 33 health research publications amid the COVID-19 pandemic in 2020 and continue to climb with 22 articles published within the first four months of 2021, the MD-PhD in Molecular Medicine Program reports.
“From the initial student publications in 2014, the number of research articles published with a UP College of Medicine-affiliated MD-PhD trainee or alumni reached 100 this year. This is a program milestone,” reported MD-PhD Program Coordinator Dr. Leslie Michelle Dalmacio and MD-PhD scholar Dr. Raniv Rojo.
Aiming to train research-oriented aspiring physicians and increase the pool of experts in biomedical research, the MD-PhD in Molecular Medicine Scholarship Program is the first and only dual degree program offered in the Philippines. It is a joint initiative of the Department of Science and Technology (DOST), Science Education Institute (SEI) through the Philippine Council for Health Research and Development (PCHRD), and the University of the Philippines (UP) College of Medicine.
The student outputs from the research courses are presented in various local and international science forums for dissemination and vetting as part of the program’s mentoring, with more substantial outputs being published.
“The DOST-PCHRD is very proud of our MD-PhD scholars for reaching this milestone at a time where the country is battling with a pandemic. This is proof that investing in education has a transformative power in boosting research and innovation for societal development,” says PCHRD Executive Director Jaime Montoya.
The PCHRD acknowledges the productivity of the MD-PhD students as shown below:
Title | MD-PhDs in Publication | DOI/URL |
Development of a loop-mediated isothermal amplification assay for detection of Trichomonas vaginalis | Reyes, John Carlo B. | https://doi.org/10.1016/j.diagmicrobio.2014.03.016 |
Leptospira-rat-human relationship in Luzon, Philippines | Zamora, Pia Regina Fatima C. | https://doi.org/10.1016/j.micinf.2014.07.001 |
Crude anthocyanin extract (CAE) from Ballatinao black rice hastens regeneration in Dugesia hymanae | Quebral, Elgin Paul B. | https://www.jpbms.info/index.php?option=com_docman&task=doc_download&gid=1206&Itemid=48 |
Not all Taua-tauas are alike: a morphological, molecular genetic, phytochemical, and anti-thrombocytopenic profiling of different Euphorbia hirta Linn. plants from the Philippines | de Paz, Sheriah Laine M.; Sumalde, Angelo Augusto M.; Cruz, Criselda Jean G.; Robles, Joyce Ann H. |
https://pjhrd.upm.edu.ph/index.php/main/article/view/26/0 |
The validity and applicability of loop-mediated isothermal amplification (LAMP) in the diagnosis of malaria in the Philippines | Poblete, Jonnel B. | https://pjhrd.upm.edu.ph/index.php/main/article/view/25 |
Crude anthocyanin extract (CAE) from Ballatinao black rice reduces acute lead toxicity in Daphnia magna | Ona, Kevin Austin L. | http://www.sciepub.com/JEPHH/abstract/4074 |
Epidemiologic study of Blastocystis infection in an urban community in the Philippines | Cadacio, Jessa Louise C. | https://doi.org/10.1155/2015/894297 |
Bioactivity of crude ethanolic and hexane extracts from Sargassum siliquosum JG agardh against fish pathogens | Tantengco, Ourlad Alzeus G. | https://doi.org/10.12692/ijb%2F6.9.55-61 |
Serologic characterization of leptospira among rats trapped in selected public markets in Iloilo City, Philippines | Zamora, Pia Regina Fatima C. | https://doi.org/10.47895/amp.v49i4.910 |
Cytotoxic activity of crude extracts and fractions from Premna odorata (Blanco), Artocarpus camansi (Blanco) and Gliricidia sepium (Jacq.) against selected human cancer cell lines | Tantengco, Ourlad Alzeus G. | https://doi.org/10.1016/j.apjtb.2015.09.011 |
Subtype analysis of Blastocystis sp. isolates from human and canine hosts in an urban community in the Philippines | Reyes, John Carlo B. | https://doi.org/10.1016/j.parint.2016.02.009 |
Effect of Lactobacillus plantarum BS25 on cholesterol levels in vitro and in BALB/c mice (Mus musculus l.) | Tumampo, Cherie Joy F. | https://pjhrd.upm.edu.ph/index.php/main/article/view/104 |
Schistosomiasis in the Philippines: Challenges and some successes in control | Tabios, Ian Kim B. | https://www.tm.mahidol.ac.th/seameo/2016-47-4/11-CPH1413p651.pdf |
Antibacterial activity of Vitex parviflora A. Juss. and Cyanthillium cinereum (L.) H. Rob. against human pathogens | Tantengco, Ourlad Alzeus G. | https://doi.org/10.1016/S2222-1808(16)61173-8 |
Nephroprotective Effects of Imperata cylindrica Root Aqueous Extract (ICRAE) on Sprague-Dawley Rats with Gentamicin-induced Acute Kidney Injury | Poblete, Jonnel B.; Santos, Bobbie Marie M. |
https://pjhrd.upm.edu.ph/index.php/main/article/view/164 |
Coconut (Cocos nucifera) Ethanolic Leaf Extract Reduces Amyloid-β (1-42) Aggregation and Paralysis Prevalence in Transgenic Caenorhabditis elegans Independently of Free Radical Scavenging and Acetylcholinesterase Inhibition | Manalo, Rafael Vincent M. | https://doi.org/10.3390/biomedicines5020017 |
The Anti-Asthmatic Effect of the Combined Yerba Buena (Mentha arvensis Linn.) and Oregano (Coleus amboinicus Lour.) Leaves in BALB/c Mice Model of Allergic Asthma | Robles, Joyce Ann H. | https://doi.org/10.47895/amp.v51i2.589 |
Association of rs17095355 Polymorphism and Extrahepatic Biliary Atresia among Filipinos | Climacosa, Fresthel Monica M. | https://doi.org/10.47895/amp.v51i3.547 |
CD14/-159 and TNFα/-308 Promoter Polymorphisms are not associated with Development of Idiopathic Neonatal Hepatitis among Filipinos | San Juan, Florence Giannina F.; Villanueva, Annavi Marie G. |
https://doi.org/10.47895/amp.v51i3.553 |
Molecular interactions with redox sites and salt bridges modulate the anti-aggregatory effect of flavonoid, tannin and cardenolide moieties against amyloid-beta (1-42) in silico | Manalo, Rafael Vincent M. | https://doi.org/10.1007/s40203-017-0033-1 |
The differential effects of atorvastatin co-administered with ampicillin on the bacterial growth and biofilm formation of Staphylococcus aureus | Manalo, Rafael Vincent M.; Josol, Vivien D. |
https://doi.org/10.1016/j.cmrp.2017.08.002 |
Anti-staphylococcal and antioxidant properties of crude ethanolic extracts of macrofungi collected from the Philippines | Tantengco, Ourlad Alzeus G. | http://dx.doi.org/10.5530/pj.2018.1.19 |
Anastasis and the ER stress response: solving the paradox of the unfolded protein response in cancer | Manalo, Rafael Vincent M. | https://doi.org/10.1016/j.mehy.2017.09.013 |
Isolation and genetic detection of pathogenic Leptospira spp. from environmental soils and water in Central Luzon, Philippines | Tantengco, Ourlad Alzeus G. | https://doi.org/10.12980/APJTD.7.2017D7-220 |
Genetic comparison of Oncomelania hupensis quadrasi (Möllendorf, 1895) (Gastropoda: Pomatiopsidae), the intermediate host of Schistosoma japonicum in the Philippines, based on 16S ribosomal RNA sequence | Tabios, Ian Kim B. | https://journals.upd.edu.ph/index.php/sciencediliman/article/view/5805 |
Ethnomycological survey of macrofungi utilized by Ayta communities in Bataan, Philippines | Tantengco, Ourlad Alzeus G. | https://www.creamjournal.org/pdf/CREAM_8_1_9.pdf |
Caffeine protects dopaminergic neurons from dopamine-induced neurodegeneration via synergistic adenosine-dopamine D2-like receptor interactions in transgenic Caenorhabditis elegans | Manalo, Rafael Vincent M. | https://doi.org/10.3389/fnins.2018.00137 |
The endoplasmic reticulum stress response in disease pathogenesis and pathophysiology | Manalo, Rafael Vincent M. | https://doi.org/10.1016/j.ejmhg.2017.07.004 |
Erythromycin exposure disrupts the life cycle stages of Aedes aegypti L. (Diptera: Culicidae) | Asis, Joannes Luke B. | https://doi.org/10.1007/s11270-018-3811-4 |
Garcinia binucao crude ethanolic leaf extract prevents alcoholinduced neurotoxic effects on learning, short-term memory, and motor functions in Drosophila melanogaster | Tantengco, Ourlad Alzeus G.; Tan, Joanne Jennifer E. |
https://www.japsonline.com/abstract.php?article_id=2747&sts=2 |
Medical students career choices and perceptions in family medicine and primary care | Tabios, Ian Kim B.; Tantengco, Ourlad Alzeus G. |
https://www.researchgate.net/publication/328281251_Medical_Students_Career_Choices_and_Perceptions_in_Family_Medicine_and_Primary_Care |
Type II restriction modification system in Ureaplasma parvum OMC-P162 strain | Tantengco, Ourlad Alzeus G. | https://doi.org/10.1371/journal.pone.0205328 |
Ethnobotanical survey of medicinal plants used by Ayta communities in Dinalupihan, Bataan, Philippines | Tantengco, Ourlad Alzeus G. | http://dx.doi.org/10.5530/pj.2018.5.145 |
Sex differences in the effects of Auricularia auricula-judae ethanolic extracts on the lifespan of Drosophila melanogaster during stress and non-stress conditions | Tantengco, Ourlad Alzeus G. | https://www.japsonline.com/abstract.php?article_id=2767 |
Antifungal activity of crude glycolated extracts of Solanum tuberosum L. (white potato) peelings against Candida and Aspergillus species | Tumampo, Cherie Joy F. | https://doi.org/10.47895/amp.v53i1.220 |
Exposure-dependent antimicrobial activity and oxidative properties of polymer-based graphene oxide nanocomposites | Perez, Joy Vanessa D.; Rojo, Raniv D. |
https://doi.org/10.4028/www.scientific.net/MSF.947.13 |
Infection rate of Schistosoma japonicum in the snail Oncomelania hupensis quadrasi in endemic villages in the Philippines: need for snail surveillance technique | Tabios, Ian Kim B.; Gampoy, Eloina Faye S. |
https://msptm.org/files/Vol36No2/402-411-Fornillos-RJC.pdf |
Association of PIK3CA and MDM2 SNP309 with cervical squamous cell carcinoma in a Philippine population | Tantengco, Ourlad Alzeus G. | https://doi.org/10.31557/apjcp.2019.20.7.2103 |
Analysis of environmental DNA and edaphic factors for the detection of the snail intermediate host Oncomelania hupensis quadrasi | Tabios, Ian Kim B. | https://doi.org/10.3390/pathogens8040160 |
Current understanding and treatment of intra-amniotic infection with Ureaplasma spp | Tantengco, Ourlad Alzeus G. | https://doi.org/10.1111/jog.14052 |
A case series of the dynamics of lipid mediators in patients with sepsis | Tantengco, Ourlad Alzeus G. | https://doi.org/10.1002/ams2.443 |
Detection of Schistosoma japonicum and Oncomelania hupensis quadrasi environmental DNA and its potential utility to schistosomiasis japonica surveillance in the Philippines | Tabios, Ian Kim B. | https://doi.org/10.1371/journal.pone.0224617 |
Current status of neglected tropical diseases (NTDs) in the Philippines | Tabios, Ian Kim B. | https://doi.org/10.1016/j.actatropica.2019.105284 |
Cytosolic non-vesicular dopamine accumulation as the predominant mechanism for developing non-DOPA responsive parkinsonism in late-stage Huntington disease | Manalo, Rafael Vincent M. | https://doi.org/10.1016/j.mehy.2019.109377 |
Mutagenicity of Bulk, Aqueous and Organic Partitions of Air Particulate Matter in Differentially Ventilated Wards in a Public Urban Hospital | Nakpil, Aurora S. | https://neptjournal.com/upload-images/NL-72-48-(46)D-843.pdf |
Fully automated preparation of 68 Ga-PSMA-11 at curie level quantity using cyclotron-produced 68Ga for clinical applications | Rojo, Raniv D. | https://doi.org/10.1016/j.apradiso.2019.108936 |
The genetics of bipolar disorder | Gordovez, Francis James A. | https://doi.org/10.1038/s41380-019-0634-7 |
First COVID-19 infections in the Philippines: a case report | Villanueva, Annavi Marie G. | https://dx.doi.org/10.1186%2Fs41182-020-00203-0 |
Antiviral effect of crude aqueous extracts from ten Philippine medicinal plants against Zika virus | Vista, Fatima Ericka S. | https://doi.org/10.47895/amp.v54i2.1501 |
A human erythrocyte-based haemolysis assay for the evaluation of human complement activity | King, Ruby Ann N.; Climacosa, Fresthel Monica M.; Santos, Bobbie Marie M. |
https://doi.org/10.1177/0261192920953170 |
COVID-19 screening on a tuberculosis ward in Manila, the Philippines | Villanueva, Annavi Marie G. | https://doi.org/10.1016/j.jctube.2020.100167 |
Macrophage HIF-1α mediates obesity-related adipose tissue dysfunction via interleukin-1 receptor-associated kinase M | Poblete, Josept Mari S. | https://doi.org/10.1152/ajpendo.00174.2019 |
Oncomelania hupensis quadrasi: snail intermediate host of Schistosoma japonicum in the Philippines | Tabios, Ian Kim B. | https://doi.org/10.1016/j.actatropica.2020.105547 |
Epidemiological and clinical characteristics of patients with suspected COVID-19 admitted in Metro Manila, Philippines | Villanueva, Annavi Marie G. | https://doi.org/10.1186/s41182-020-00241-8 |
In vivo performance of gold nanoparticle-loaded absorbable inferior vena cava filters in a swine model | Perez, Joy Vanessa D. | https://doi.org/10.1039/d0bm00414f |
Novel variants in hearing loss Genes and associations with audiometric thresholds in a multi-ethnic cohort of US patients with cochlear implants | Sumalde, Angelo Augusto M. | https://doi.org/10.1097/mao.0000000000002671 |
Detection of human pegivirus (HPgV) infection among Filipino children with decompensated liver disease secondary to biliary cirrhosis and liver transplant pediatric patients | Aquino, Inah Marie C. | https://doi.org/10.47895/amp.v54i4.1897 |
COVID-19 screening for healthcare workers in a tertiary infectious diseases referral hospital in Manila, the Philippines | Villanueva, Annavi Marie G. | https://doi.org/10.4269/ajtmh.20-0715 |
Prevalence of urolithiasis by ultrasonography among patients with gout: a cross-sectional study from the UP-Philippine General Hospital | Abrilla, Aedrian A. | https://doi.org/10.2147/rru.s268700 |
Genomic and proteomic mutation landscapes of SARS‐CoV‐2 | Badua, Christian Luke D.C; Baldo, Karol Ann T. |
https://doi.org/10.1002/jmv.26548 |
Detection of Vibrio parahaemolyticus in fish samples from selected wet markets in Laguna, Philippines, using loop-mediated isothermal amplification (LAMP) and real-time polymerase chain reaction (qPCR) | Teh, Treena Rica D. | https://www.philsciletters.net/2020-special-issue-8/ |
Prevalence of Entamoeba histolytica and Entamoeba dispar among residents of an urban slum area in Manila, Philippines as detected by the polymerase chain reaction | Aquino, Inah Marie C. | https://annals-parasitology.eu/go.live.php/download_default/D1729/prevalence-of-ientamoeba-histolyticai-and-ientamoeba-dispari-among-residents-of-an-urban-slum-area-in-manila-philippines-as-detected-by-the-polymerase-chain-reaction.html |
Understanding nanoparticle toxicity to direct a safe-by-design approach in cancer nanomedicine | Perez, Joy Vanessa D. | https://doi.org/10.3390/nano10112186 |
Effects of a gestational level of estradiol on cellular transition, migration, and inflammation in cervical epithelial and stromal cells | Tantengco, Ourlad Alzeus G. | https://doi.org/10.1111/aji.13370 |
Environmental pollutant exposure can exacerbate COVID-19 neurologic symptoms | Reyes, Michael Sigfrid S. | https://doi.org/10.1016/j.mehy.2020.110136 |
Development and characterization of polymeric peptides for antibody tagging of bacterial targets | Climacosa, Fresthel Monica M.; King, Ruby Ann N.; Santos, Bobbie Marie M. |
https://doi.org/10.2174/0929866527666200427212940 |
Hydranencephaly: clinical features and survivorship in a retrospective cohort | Reyes, John Carlo B. | https://doi.org/10.1016/j.wneu.2020.09.029 |
Radiopaque scaffolds based on electrospun iodixanol/polycaprolactone fibrous composites | Perez, Joy Vanessa D.; Rojo, Raniv D. |
https://doi.org/10.1016/j.mtla.2020.100874 |
Primary Care Orientation of Family Practice in the Philippines: Cross-sectional Study in Pilot Sites | Tabios, Ian Kim B. | https://www.researchgate.net/profile/Leilanie-Nicodemus-2/publication/348758671_Primary_Care_Orientation_of_Family_Practice_in_the_Philippines_Cross-sectional_Study_in_Pilot_Sites/links/600fb2a4299bf14088c09375/Primary-Care-Orientation-of-Family-Practice-in-the-Philippines-Cross-sectional-Study-in-Pilot-Sites.pdf |
Identification of Class I HLA alleles in anonymized cell therapy specimens through real-time PCR with meltcurve analysis | Tan, Joanne Jennifer E. | https://www.psbmb.org/uploads/1/0/1/3/101342864/article_4_january-december_2020_volume_1_issue_1_2.pdf |
Contractile function of the cervix plays a role in normal and pathological pregnancy and parturition | Tantengco, Ourlad Alzeus G. | https://doi.org/10.1016/j.mehy.2020.110336 |
Caffeine reduces deficits in mechanosensation and locomotion induced by L-DOPA and protects dopaminergic neurons in a transgenic Caenorhabditis elegans model of Parkinson’s disease | Manalo, Rafael Vincent M. | https://doi.org/10.1080/13880209.2020.1791192 |
Policy analysis on determining hospital bed capacity in light of Universal Health Care | Buan, Ara Karizza G. | https://doi.org/10.47895/amp.v54i6.2596 |
A call for an evidence-informed criteria selection to guide equitable health investments in the era of Universal Health Care: policy analysis | Buan, Ara Karizza G. | https://doi.org/10.47895/amp.v54i6.2587 |
Addressing primary care inequities in underserved areas of the Philippines: a review | Buan, Ara Karizza G. | https://doi.org/10.47895/amp.v54i6.2578 |
In silico prediction of SARS-CoV-2 epitopes for vaccine development | Marco, Kitz Paul D.; Llagas, Julia Patricia B. |
https://pjhrd.upm.edu.ph/index.php/main/article/view/382 |
An optimized de Man Rogosa Sharpe-McCoy’s 5A medium formulation for the in vitro screening of cytotoxic effects by probiotic candidates against colorectal cancer cells | Badua, Christian Luke D.C | https://www.philsciletters.net/2020-139/ |
Molecular epidemiology of coxsackievirus A6 causing hand-foot-and-mouth disease in the Philippines, 2012–2017 | Climacosa, Fresthel Monica M. | https://doi.org/10.1016/j.ijid.2020.09.1299 |
Optimization of the differentiation and quantification of high-Z nanoparticles incorporated in medical devices for CT-guided interventions | Perez, Joy Vanessa D. | https://doi.org/10.1002/mp.14601 |
Recent advances in nanomedicine for the diagnosis and treatment of prostate cancer bone metastasis | Perez, Joy Vanessa D.; Rojo, Raniv D. |
https://doi.org/10.3390/molecules26020384 |
Effects of brief adjunctive metformin therapy in virologically suppressed HIV-infected adults on polyfunctional HIV-specific CD8 T cell responses to PD-L1 blockade | Padua, Ana Joy P. | https://doi.org/10.1089/aid.2020.0172 |
Revealing the anticancer potential of candidate drugs in vivo using Caenorhabditis elegans mutant strains | Cruz, Christian Alfredo K. | https://doi.org/10.1016/j.tranon.2020.100940 |
The role of genital mycoplasma infection in female infertility: a systematic review and meta-analysis | Tantengco, Ourlad Alzeus G. | https://doi.org/10.1111/aji.13390 |
Anti-inflammatory drugs and the renin-angiotensin-aldosterone system: current knowledge and potential effects on early SARS-CoV-2 infection | Manalo, Rafael Vincent M. | https://doi.org/10.1016/j.virusres.2020.198190 |
Barriers to online learning in the time of COVID-19: a national survey of medical students in the Philippines | Reyes, John Carlo B. | https://doi.org/10.1007/s40670-021-01231-z |
Virgin coconut oil attenuates deficits in rats undergoing transient cerebral ischemia | Climacosa, Fresthel Monica M. | https://doi.org/10.47895/amp.v55i1.2938 |
Philippine rice wine (tapuy) made from Ballatinao black rice and traditional starter culture (Bubod) showed high alcohol content, total phenolic content, and antioxidant activity | Dela Rosa, Jared Gabriel L. | https://doi.org/10.1590/fst.45120 |
Evaluation of crude adult Ascaris suum intestinal tract homogenate in inducing protective IgG production against A. suum larvae in BALB/c mice | Girasol, Mark John G.; Grecia, Lordom Reno C. |
https://doi.org/10.1016/j.exppara.2020.108049 |
Direct saliva versus conventional nasopharyngeal swab qRT-PCR to diagnose SARS – CoV2: validity study | Abrilla, Aedrian A. | https://doi.org/10.9734/ajrid/2021/v6i230193 |
Cactus: chemical, nutraceutical composition and potential bio-pharmacological properties | Tantengco, Ourlad Alzeus G. | https://doi.org/10.1002/ptr.6889 |
Oxidative stress promotes cellular damages in the cervix: implications for normal and pathologic cervical function in human pregnancy | Tantengco, Ourlad Alzeus G. | https://doi.org/10.1093/biolre/ioab058 |
If not COVID-19 what is it? Analysis of COVID-19 versus common respiratory viruses among symptomatic health care workers in a tertiary infectious disease referral hospital in Manila, Philippines | Villanueva, Annavi Marie G. | https://doi.org/10.3390/tropicalmed6010039 |
Molecular epidemiologic analysis of Mycobacterium tuberculosis among prison inmates in selected prisons in the Philippines | Malabad, John Carlo M. | https://philjournalsci.dost.gov.ph/images/pdf/pjs_pdf/vol150no2/molecular_epidemiologic_analysis_of_mycobacterium_tuberculosis_.pdf |
Molecular epidemiology of Mycobacterium tuberculosis in adult Filipino TB-HIV co-infected patients | Malabad, John Carlo M. | https://doi.org/10.5588/ijtld.20.0878 |
Organ-on-chip of the cervical epithelial layer: A platform to study normal and pathological cellular remodeling of the cervix | Tantengco, Ourlad Alzeus G. | https://doi.org/10.1096/fj.202002590rrr |
Progesterone alters human cervical epithelial and stromal cell transition and migration: Implications in cervical remodeling during pregnancy and parturition | Tantengco, Ourlad Alzeus G. | https://doi.org/10.1016/j.mce.2021.111276 |
Combinatorial effect of radium-223 and irreversible electroporation on prostate cancer bone metastasis in mice | Rojo, Raniv D.; Perez, Joy Vanessa D. |
https://doi.org/10.1080/02656736.2021.1914873 |
Prevalence and prognostic associations of cardiac abnormalities among hospitalized patients with COVID‐19: a systematic review and meta‐analysis | Lintao, Ryan C.V. | https://doi.org/10.1038/s41598-021-87961-x |
Efficacy of fluvastatin and aspirin for prevention of hormonally insensitive breast cancer | Rojo, Raniv D. | https://doi.org/10.1007/s10549-021-06229-0 |
Plant Species of Sub-Family Valerianaceae—A Review on Its Effect on the Central Nervous System | Tantengco, Ourlad Alzeus G.; Robles, Joyce Ann H. |
https://doi.org/10.3390/plants10050846 |
Metformin extended-release versus metformin immediate-release for adults with type 2 diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials | Abrilla, Aedrian A. | https://doi.org/10.1016/j.diabres.2021.108824 |
Characteristics and Factors Associated with Mortality of 200 COVID-19 Patients at a Philippine COVID-19 Tertiary Referral Center | Poblete, Jonnel B. | https://doi.org/10.47895/amp.v55i2.2845 |