Hepa B poster (Photo by eagron)

The Philippine Council for Health Research and Development of the Department of Science and Technology (PCHRD-DOST) conducted a seminar on “Code Yellow, Mission Against Hepatitis” to draw awareness on the dreadful disease on 30 January 2012.


“Yellow because patients with hepatitis usually manifest yellowish pigmentation of the skin. Code yellow means, we are exposing the information on hepatitis to increase the community’s awareness on the disease,” said Dr. Lemuel Delos Reyes, General Medicine practitioner and Hepatitis B Awareness Campaign advocate during the seminar.

Hepatitis is an inflammation of the liver, most commonly caused by a viral infection. The disease has five different types, hepatitis A, B, C, D and E. In particular, types B and C lead to chronic disease in hundreds of millions of people and are the most common cause of liver cirrhosis and cancer.

Hepatitis A and E are typically caused by ingestion of contaminated food or water. Hepatitis B, C and D usually occur as a result of parenteral contact with infected body fluids. Common modes of transmission include receipt of contaminated blood or blood transfusion, sexual intercourse, sharing of inanimate objects such as wash cloth, towels, toothbrushes, razors, among others. The disease can also be transmitted through prenatal exposure to an infected mother.

Acute infection may occur with limited or no symptoms. Among the symptoms include jaundice (yellowing of the skin and eyes), dark or “tea-like” urine, extreme fatigue, nausea, vomiting, abdominal pain and loss of appetite.

The disease is a serious public health issue because it is highly contagious and easily transmitted. It is also of greatest concern because of the burden of illness and death it cause and the potential for outbreaks and epidemic spread.

According to the Hepatitis B Foundation Institute for Hepatitis and Virus Research, More than 2 billion people worldwide have been infected by hepatitis B Virus (HBV) and 1 million people die each year.

In the Philippines, the World Health Organization (WHO) reported that 60 percent of Filipinos have been infected with HBV while approximately 10 percent of Filipinos have chronic or active Hepatitis–B and are virus carriers. “This means that there are already around 8-10 million Hepatitis-B carriers in the country who might infect more people,” revealed Dr. Delos Reyes.

“We are all at risk. Though the disease has no cure yet, it is highly preventable,” said Dr. Delos Reyes.

Aside from proper hygiene and sanitation, vaccination is an important way to prevent the disease. “Vaccination is the easiest and most logical means of preventing the disease. It is also recognized as the most effective and long term means of preventing hepatitis,” said Dr. Delos Reyes.


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PCHRD Calls for health research proposal

The Philippine Council for Health Research and Development of the Department of Science and Technology (PCHRD-DOST) encourages researchers from public and private institutions to submit health R&D proposals for possible funding.

Proposals to be submitted should be aligned with the research priorities of PCHRD, specifically health technology development part of the National Unified Health Research Agenda (NUHRA), 2011-2016. These include drug discovery and development, development of diagnostic kits for priority diseases, genomics and molecular technology, functional foods, hospital equipment and biomedical devices, information and communication technology (ICT) in health, and chronobiology.

Drug discovery include studies on natural substances from herbal, marine and other terrestrial sources for potential drug applications in the treatment of common infectious diseases and other lifestyle-related disorders.

Researches on the development of diagnostic kits include the production of diagnostic tests for priority infectious and lifestyle-related diseases. Priority diseases are dengue and dengue-like illnesses, drug-resistant malaria, drug resistant tuberculosis, influenza-like illnesses, leptospirosis and sepsis for infectious diseases and myocardial infarction, colorectal cancer, stroke, diabetes mellitus, and breast cancer for non-infectious diseases.

Studies on genomics and molecular technology focus on the utilization and application of information in the human genome in the design and discovery of vaccines, therapeutics, diagnostic devices and products.

Studies on functional foods cover researches on the health benefits and safety assessment of food or food components which aim to reduce the risks of disease occurrence, specifically for lifestyle-related diseases such as cardiovascular diseases (CVD), diabetes, and cancer.

Researches on hospital equipment and biomedical devices focus on the development of affordable, safe and reliable hospital equipment and biomedical devices for diagnosis, therapy and surgery, which can be mass-manufactured locally. These include ventilators or respirators, operating room (OR) lights, anesthesia machines, prosthesis, minimally invasive surgical equipment and instruments and rehabilitation equipment.

ICT in health studies involve the development of user-friendly ICT solutions to accelerate the gathering and processing of health and related information for policy making and delivery of quality healthcare services. ICT on health topics may include public health surveillance or health intelligence systems, telehealth services, interface for ICT-enabled medical devices and ICT-enabled services.

Chronobiology researches look into the alleged health related risks of shift-works among shift-workers. Chronobiology came to public awareness because of the increasing call center and business process outsourcing (BPO) industries in the country that employs thousands of Filipino workers.

Proposals will be evaluated according to their technical merit, data management, relevance/significance, marketability potentials for product-based research, feasibility and the proponent’s institutional capacity.

The 1st Scientific Symposium on the Prevention and Control of Leptospirosis in the Philippines offered a chance for the listeners to ask questions to the speakers about the researches presented.

The University of the Philippines Manila – College of Public Health (UPM-CPH) hosted the 1st Scientific Symposium on the Prevention and Control of Leptospirosis in the Philippines (LepCon), at the UPM-CPH Auditorium on the 26th of January 2012.

This year's symposium covered ten papers published by the ten Filipino and Japanese scientists in leptospirosis research under the LepCon program. Four working groups presented the progresses made in each of their respective studies. Working Group A talked about the surveillance of the disease and the creation of diagnostic kits and vaccines for leptospirosis. Working Group B presented the studies made in the burden of disease. Working Group C showed the results of their research on the environmental factors in transmission and outbreaks of leptospirosis. Working Group D discussed health promotion and advocacy concerning leptospirosis in the Philippines. Ten scientists who led each research in each working group attended the event as speakers.

LepCon is a collaborative effort of the UPM-CPH, Kyushu University (KU), and the Japan International Cooperation Agency (JICA), with the support of the World Health Organization (WHO) and the Philippine Council for Health Research and Development of the Department of Science and Technology (PCHRD-DOST).

In his opening remarks, Dr. Jaime C. Montoya, Executive Director of the PCHRD-DOST, stressed that the symposium should serve as an inspiration to the researchers to choose leptospirosis as the field of their study.

He said, “I hope that with these presentations, we would be able to inspire and encourage other researchers, especially the young, to pursue this field of interest because it will severely and importantly affect the majority of Filipinos.”

Dr. Priscilla Torres, Dean of the UST Faculty of Pharmacy (right) hands over the certificate of appreciation to PCHRD's RDMD Chief Dr. Antonio Ligsay (Center).

The Philippine Council for Health Research and Development of the Department of Science and Technology (PCHRD-DOST) joins the celebration of Science Week 2012 of the College of Sciences, University of Santo Tomas (UST) in Sampaloc, Manila last 6 February 2012.

The five-day celebration with the theme “Building a Healthier Environment through Science” featured science lectures, research poster exhibits, and interactive exhibits on mathematics, physics, biology, chemistry, microbiology and psychology.

In her opening message, Professor Elena Manansala, Assistant Dean of UST Faculty of Pharmacy said that the event will encourage graduating students to do relevant researches that will impact the community. “It is also an avenue to make our students aware on the researches undertaken by the university and effective way of cultivating research culture to prepare students to become productive member of the research community.”

Dr. Antonio Ligsay, Chief of the PCHRD’s Research Development and Management Division, served as reactor and keynote speaker. In his message, Dr. Ligsay motivated students to participate in discovering new knowledge through health research and development (R&D). “With those outputs you presented in the exhibits, I believe you have great potential to be part of the national endeavor to address health issues and problems of the country. Fresh minds usually have fresh ideas and we want to hear from you. If you have potential ideas for research - approach your institution’s faculty members, because together we can make the Filipino life better through health R&D.”


Dr. Ligsay also discussed the PCHRD research evaluation processes, submission of research proposal for funding and the policies and directions for health research. “PCHRD research priorities include genomics, drug discovery and development, studies on functional foods, hospital equipment and biomedical devices, ICT in health and chronobiology. Along with these priorities, we can maximize our creativity and keen ideas for research to seek for new technologies, products and innovations.”

UST is one of the member institutions of the Metro Manila Health Research and Development Consortia (MMHRDC) of the Philippine National Health Research System (PNHRS).

The Philippine Health Research Ethics Board (PHREB), together with Forum for Ethical Review Committees in the Asian and Western Pacific Region (FERCAP), held an Advance Training for Surveyors and Accreditors on ethical review practices from January 30 to February 8, 2012. The primary objective of the training was to promote good ethical review practices in health research in the Asia and Pacific region by implementing international criteria for surveying and evaluating ethical review practices.

Scope of the training included the following areas: (a) training and certification of in-country surveyors of ethical review practices; (b) translation and in-country adaptation of the Surveying and Evaluating Ethical Review Practices guideline; (c) development of in-country and regional standards for recognition of ethical review committees; and (d) development of international human subject protection standards.

In the workshop, the participants were divided into working groups, each group with one facilitator. Working groups carried out an evaluation of the ethics committees of research institutions. The last days of the training were devoted to site visits: February 1-3 at the Philippine Heart Center and February 6-8 at the Medical City.

Members and affiliates of Asian and Western Pacific Ethics Committee participated in the training.  Lead surveyors and coordinators were Dr. Cristina E. Torres (FERCAP), Dr. Cecilia Tomas (PHREB), Ms. Julia Lu, Dr. Marita Reyes, Dr. Salome Vios, and Asst. Prof. Edlyn Jimenez.